REBAMIPIDE(mucoprotective agent)

EROSIVE GASTRITIS

Before understand about rebamipide we should know about Erosive gastritis.

chemical class of quinolinone derivatives.

Erosive gastritis is a inflammation and erosion of the lining of the stomach. This erosion can lead to painful ulcers and bleeding. Here are some key points about erosive gastritis:

  1. Causes:
    • NSAIDs: Nonsteroidal anti-inflammatory drugs (NSAIDs) like aspirin, ibuprofen, and naproxen are common causes. Prolonged use of these medications can irritate the stomach lining.
    • Alcohol: Excessive alcohol consumption can lead to erosive gastritis.
    • Stress: Severe physical stress from illness, surgery, or trauma can lead to erosive gastritis.
    • Bile Reflux: When bile backs up into the stomach, it can cause irritation and erosion of the lining.
    • Infections: Helicobacter pylori bacteria can cause gastritis and, if left untreated, may lead to erosive gastritis.

Rebamipide is DRUG that is used to treat various gastrointestinal disorders. It is known for its mucoprotective and anti-inflammatory properties.

Rebamipide belongs to a class of drugs known as mucoprotective agents

  1. Mechanism of Action: Rebamipide works by increasing the production of mucin, a natural protective substance that lines the stomach and intestines. It also has anti-inflammatory effects which can help reduce inflammation in the gastrointestinal tract. It also works as antioxident

2.Medical Uses:

  1. Side Effects– Common side effects may include gastrointestinal upset, diarrhea, dizziness, and skin rash. second bioavailability is not high.
  2. Dosage– The dosage of rebamipide can vary depending on the specific condition being treated, the severity of the condition, and individual patient factors.
  3. Precautions
    • Pregnant or breastfeeding individuals should consult their healthcare provider before using this medication.
  4. Availability: Rebamipide may be available in various forms, including tablets and oral suspension.

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